Hi!
Well, the noise can originate from tranistors, diodes, and in some rarer circumstances - any other component. While you can get the replacements or even original (NOS) transistors and diodes, there is very slim chance that there is a replacement for IC. As it was brought before on this forum, IC's are often designed for specific task, sometimes even for specific box.
I would first take the schematic and instruments. Measure the hiss (noise with no other signal or weak signal (e.g. sine 1kHz) ) from the speaker all the way up to the source of the signal. This is by no means easy and straightforward, and takes time.
On the othr hand, there are some components that are known to go bad and produce problems. You could also try searching the 'net using the component list, even before you open the box. Perhaps that could help, or lead you to waste hours and hours searching for the gost in the machine... or Gremlins, as my friend would say.